Title:
フリーラジカル―誘発状態を治療するためのキレート化剤およびその金属キレート
Document Type and Number:
Japanese Patent JP4162263
Kind Code:
B2
Abstract:
The invention relates to the use of certain chelating agents and their metal chelates and to the use of certain manganese containing compounds, in particular manganese chelates, in the manufacture of a therapeutic agent for use in reducing the cardiotoxicity of an antitumor agent. Such compounds are particularly effective in reducing the side-effects of anthracycline drugs and/or paclitaxel.
Inventors:
Carlsson, Jean, Olaf, Gustav
Jung, Par
Twart, Robertson
Jung, Par
Twart, Robertson
Application Number:
JP50255898A
Publication Date:
October 08, 2008
Filing Date:
June 24, 1997
Export Citation:
Assignee:
GE Healthcare Aksuye Sersukapu
International Classes:
A61K31/675; A61K31/198; A61K45/00; A61K31/28; A61K31/337; A61K31/44; A61K31/4415; A61K31/444; A61K31/661; A61K31/704; A61K33/32; A61P9/00; A61P9/10; A61P39/04
Domestic Patent References:
| JP8026902A | ||||
| JP7126176A | ||||
| JP63280087A | ||||
| JP63287791A | ||||
| JP64066117A | ||||
| JP8504211A | ||||
| JP1265018A |
Other References:
THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1994年, Vol.271,No.2, 609-614
INVESTIGATIVE RADIOLOGY, 1997年 4月, Vol.32,No.4, 205-211
INVESTIGATIVE RADIOLOGY, 1997年 4月, Vol.32,No.4, 205-211
Attorney, Agent or Firm:
Kenichi Matsumoto
Hirokazu Ogura
Toshihisa Kurokawa
Shunichiro Suzuki
Hirokazu Ogura
Toshihisa Kurokawa
Shunichiro Suzuki