Title:
FULLERENE-BINDING WATER-SOLUBLE POLYMER PHOTOSENSITIZER FOR PHOTODYNAMIC THERAPY
Document Type and Number:
Japanese Patent JPH09235235
Kind Code:
A
Abstract:
To obtain a photosensitizer for the photodynamic therapy by chemically modifying fullerene with a water-soluble polymer.
Fullerene is made soluble in water and given the cancer tissue- targeting properties after its intravenous administration. The difference in disappearance pattern of accumulated fullerenes from the tissues is cleverly utilized to increase the concentration difference between the normal tissues and the cancer tissues and the photodynamic therapy effect that only cancer tissues can be broken by radiation with light is recognized. Thus, the fullerene-water- soluble polymer binder can be expected to be used as a photosensitizer for the photodynamic therapy.
Inventors:
IKADA YOSHITO
TABATA YASUHIKO
NAKAJIMA NAOKI
TABATA YASUHIKO
NAKAJIMA NAOKI
Application Number:
JP8444996A
Publication Date:
September 09, 1997
Filing Date:
February 29, 1996
Export Citation:
Assignee:
PROD DEV RES INST
International Classes:
A61K33/44; A61K47/32; A61P43/00; A61K9/00; (IPC1-7): A61K33/44; A61K33/44; A61K9/00; A61K47/32
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