Title:
G-PROTEIN PARATHYROID HORMONE RECEPTOR HLTDG74
Document Type and Number:
Japanese Patent JP2003033192
Kind Code:
A
Abstract:
To identify an antagonist to or an agonist for a therapeutically usable polypeptide for inhibiting or stimulating a human G-protein parathyroid hormone(PTH) receptor.
The human G-protein parathyroid hormone(PTH) receptor is expressed on the surface of a cell, the cell is contacted with a receptor ligand and a compound to be screened, and whether the secondary signal is generated from the interaction between the ligand and the receptor is determined; further, whether the compound to be screened is an agonist or antagonist is identified.
Inventors:
DANIEL R SOPETTO
RI I
ROSEN CRAIG A
RUBEN STEVEN M
RI I
ROSEN CRAIG A
RUBEN STEVEN M
Application Number:
JP2002137833A
Publication Date:
February 04, 2003
Filing Date:
June 05, 1995
Export Citation:
Assignee:
HUMAN GENOME SCIENCES INC
International Classes:
C12N15/09; A61K38/00; A61K48/00; A61P3/14; A61P5/00; A61P13/12; A61P19/10; A61P43/00; (IPC1-7): C12N15/09; A61K48/00; A61P3/14; A61P5/00; A61P13/12; A61P19/10; A61P43/00
Attorney, Agent or Firm:
Shusaku Yamamoto (2 outside)
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