Title:
遺伝子発現プロファイル及び乳癌におけるその使用
Document Type and Number:
Japanese Patent JP6931926
Kind Code:
B2
Abstract:
A method for predicting the likelihood of locoregional recurrence (LRR) and/or distant metastasis in a subject with breast cancer following mastectomy and/or breast conserving surgery, comprising: measuring the expression level of at least one gene in a sample isolated from the subject; and deriving a score based on the measured expression level of the at least one gene, wherein the at least one gene is selected from a group consisting of TRPV6, DDX39, BUB1B, CCR1, STIL, BLM, C16ORF7, TPX2, PTI1, TCF3, CCNB1, DTX2, PIM1, ENSA, RCHY1, NFATC2IP, OBSL1, and MMP15, and wherein the derived score provides an indication of the likelihood of LRR and/or the likelihood of distant metastasis in the subject.
Inventors:
Cheng Han-Chung
Application Number:
JP2017560653A
Publication Date:
September 08, 2021
Filing Date:
May 19, 2016
Export Citation:
Assignee:
Amwise Diagnostic Private Limited
International Classes:
C12Q1/6851; C12M1/00; C12N15/09; C12Q1/6837; C12Q1/686; G16B40/20
Domestic Patent References:
| JP2010516292A | ||||
| JP2005270093A | ||||
| JP2007527220A |
Foreign References:
| WO2014066796A2 | ||||
| WO2012079059A2 |
Other References:
Journal of Clinical Oncology, 2006, Vol.24, pp.4594-4602
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office