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Title:
ENZYMATIC PERACID GENERATION FOR USE IN ORAL CARE PRODUCTS
Document Type and Number:
Japanese Patent JP2017081958
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide compositions and methods to treat an oral cavity surface with a peracid-based benefit agent.SOLUTION: A composition separately comprises a source of peroxygen, e.g. peracetic acid, and CE-7 carbohydrate esterase (perhydrolase) having perhydrolytic activity. A peroxyacid is enzymatically produced from a carboxylate ester substrate in the mouth by the enzyme. A peroxyacid benefit agent can be used for bleaching, whitening, disinfection, bleaching, deodorization, and reduction or removing of a biofilm on the surface of the oral cavity, and combinations thereof. In addition, perhydrolysis activity can be targeted to the oral cavity surface using a fusion protein comprising the perhydrolase which is coupled to a peptidic component having affinity for an oral cavity surface, either directly or through an optional linker.SELECTED DRAWING: None

Inventors:
LISA A BUTTERICK
SCOTT D CUNNINGHAM
ROBERT DICOSIMO
KARI A FOSSER
TANJA MARIA GRUBER
SHARON L HAYNIE
PAYNE MARK S
PIERRE E ROUVIERE
WANG HONG
Application Number:
JP2016248580A
Publication Date:
May 18, 2017
Filing Date:
December 22, 2016
Export Citation:
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Assignee:
DU PONT
International Classes:
A61K8/66; A61K8/37; A61K8/38; A61K8/60; A61Q11/00; C07K7/00; C07K14/00; C07K19/00
Domestic Patent References:
JP2010512165A2010-04-22
JP2010512165A2010-04-22
JP2008512372A2008-04-24
JP2008512372A2008-04-24
JP2010512165A2010-04-22
Foreign References:
US20090311198A12009-12-17
US20090311198A12009-12-17
WO2010117753A22010-10-14
WO2010019544A12010-02-18
US20100247457A12010-09-30
WO2010117753A22010-10-14
WO2010019544A12010-02-18
US20100247457A12010-09-30
US20090311198A12009-12-17
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi