To provide a gene related to carbohydrate metabolism and/or lipid metabolism, to provide a protein encoding the gene, to provide a method for detecting carbohydrate metabolism abnormality and lipid metabolism abnormality with the gene or the protein, to provide a method for testing a substance for improving the carbohydrate metabolism abnormality and lipid metabolism abnormality with the gene or the protein, to provide a substance for improving the carbohydrate metabolism abnormality and the lipid metabolism abnormality, and to provide the like.
A polynucleotide capable of being remarkably reduced by the administration of an insulin resistance-improving agent using a nuclear receptor, PPARγ, as a target molecule, a protein encoding the polynucleotide, and an antibody therefor are used.
COPYRIGHT: (C)2004,JPO
Suga Suga
Jun Osumi
Manabu Abe
Araki Kazushi
Arch.Histol.Cytol.,2001年,Vol.64,p.319-327
FEBS Letters,1997年,Vol.401,p.218-222
FEBS Letters,1999年,Vol.462,p.129-134
Toshiaki Yaguchi
Yuki Echigo