Title:
ＦＧＦ−１８化合物に対する応答性を予測するための遺伝子マーカー
Document Type and Number:
Japanese Patent JP6496003
Kind Code:
B2
Abstract:
This application is directed to the use of biomarkers for predicting the sensitivity to treatment with an FGF-18 compound of a patient having a cartilage disorder, such as osteoarthritis, cartilage injury, fractures affecting joint cartilage or surgical procedures with impact on joint cartilage (e.g., microfracture), in order to reduce the risk of adverse events and increase the overall benefit after therapy.
Inventors:
Christoph Hubertus Radel
Alix Anne Zimone Belton
Armand Barcésia
Pierre Jack Falmer
Alix Anne Zimone Belton
Armand Barcésia
Pierre Jack Falmer
Application Number:
JP2017236167A
Publication Date:
April 03, 2019
Filing Date:
December 08, 2017
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
A61K38/18; A61P19/08
Domestic Patent References:
| JP2011520433A | ||||
| JP2010501531A | ||||
| JP6262731B2 |
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Kazumi Nakamura
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Kazumi Nakamura