GENETIC POLYMORPHISM ASSOCIATED WITH CARDIOVASCULAR DISORDER AND DRUG RESPONSE, METHOD OF DETECTION AND USE THEREOF

Title:

GENETIC POLYMORPHISM ASSOCIATED WITH CARDIOVASCULAR DISORDER AND DRUG RESPONSE, METHOD OF DETECTION AND USE THEREOF

Document Type and Number:

Japanese Patent JP2013135671

Kind Code:

A

Abstract:

To provide a method for identifying an individual having an altered risk for developing an acute coronary event or a method for evaluating an individual's likelihood of responding to statin treatment.

The method for identifying an individual having an altered risk of developing an acute coronary event or a method for evaluating an individual's likelihood of responding to statin treatment, comprises a step of detecting the presence or absence of one or more alleles of an SNP in the individual's nucleic acids, wherein the SNP is selected from any one of three specific nucleotide sequences, and the presence or absence of the alleles are correlated with an individual's risk of developing the acute coronary event or likelihood of responding to statin treatment.

Inventors:

IAKOUBOVA OLGA
DEVLIN JAMES J

Application Number:

JP2013002486A

Publication Date:

July 11, 2013

Filing Date:

January 10, 2013

Export Citation:

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Assignee:

CELERA CORP

International Classes:

C12N15/09; C07K16/18; C12Q1/68; G01N33/15; G01N33/50; G01N33/53

Foreign References:

WO2005056837A2

2005-06-23

Other References:

JPN6012006263; Ｊｏｕｒｎａｌ　ｏｆ　ｔｈｅ　Ａｍｅｒｉｃａｎ　Ｃｏｌｌｅｇｅ　ｏｆ　ＣａｒｄｉｏｌｏｇｙＶｏｌ．５３，　Ｎｏ．１６, 2009, ｐｐ．１４７１-１４７２
JPN6012006261; 'Ｓｕｂｍｉｔｔｅｄ　ＳＮＰ（ｓｓ）　Ｄｅｔａｉｌｓ：　ｓｓ２３８９９９６６，　Ａｕｇ　２０　２００４　ｓｕｂｍｉｔｔｅｄ' Ｄａｔａｂａｓｅ　ＮＣＢｌ　ｄｂＳＮＰ　Ｓｈｏｒｔ　Ｇｅｎｅｔｉｃ　Ｖａｒｉａｔｉｏｎｓ［ｏｎｌｉｎｅ］，　Ａｃｃｅｓｓｉｎ　Ｎｏ．ｓｓ２３８９９９６６ , 20120201

Attorney, Agent or Firm:

Hidesaku Yamamoto
Natsuki Morishita

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