Title:
遺伝的に操作された細胞培養適応感染性嚢胞疾患ウイルス(IBDV)突然変異体
Document Type and Number:
Japanese Patent JP4675447
Kind Code:
B2
Abstract:
The present invention relates to a method for the adaptation of infectious bursal disease viruses (IBDV) to growth in CEF cell culture. Changing the codons for amino acid residues 253 (Gln) and 284 (Ala) to 253 (His) and 284 (Thr) allowed bursa adapted Classical and Variant-E IBDV to grow in CEF cell culture. For GLS IBDV only a change of the codon for amino acid residue 284 was necessary.
Inventors:
Adrien Antonius Wilhelms Maria Juan Lone
Egbert Mund
Egbert Mund
Application Number:
JP2000057146A
Publication Date:
April 20, 2011
Filing Date:
March 02, 2000
Export Citation:
Assignee:
Interventional Internal Bee
International Classes:
C12N15/09; A61K39/12; A61P31/12; C07K14/08; C12N5/10; C12N7/00; C12N15/00; C12N15/01; C12N15/12; C12P21/02
Domestic Patent References:
| JP9510873A |
Other References:
Virology,1996年,Vol.223,p.219-223
Attorney, Agent or Firm:
Yoshio Kawaguchi
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura