Title:
GLUCOCORTICOID RECEPTOR MODULATOR
Document Type and Number:
Japanese Patent JP2009046435
Kind Code:
A
Abstract:
To obtain a prophylactic and/or a therapeutic agent for autoimmune diseases and allergic diseases, which has a selective binding activity to a glucocorticoid receptor, an alleviated adverse effect derived from a progesterone receptor and a mineralocorticoid receptor and high safety.
The condensed tetrahydroquinoline compound is represented by the general formula (I), and its pharmacologically acceptable salt, its hydrate or solvate is provided. Consequently, the prophylactic and/or the therapeutic agent for autoimmune diseases and allergic diseases has a selective binding activity to a glucocorticoid receptor, an alleviated adverse effect derived from a progesterone receptor and a mineralocorticoid receptor and high safety.
Inventors:
EDA MASAHIRO
KUSAKA SHINICHI
NAGAOKA KAZUHIKO
AOKI YOSHIYUKI
MURAKAMI KAZUKI
KAGOTA NARIYASU
KOBAYASHI FUJIO
KUSAKA SHINICHI
NAGAOKA KAZUHIKO
AOKI YOSHIYUKI
MURAKAMI KAZUKI
KAGOTA NARIYASU
KOBAYASHI FUJIO
Application Number:
JP2007214523A
Publication Date:
March 05, 2009
Filing Date:
August 21, 2007
Export Citation:
Assignee:
MITSUBISHI TANABE PHARMA CORP
International Classes:
C07D221/16; A61K31/4375; A61K31/444; A61K31/473; A61K31/497; A61K31/4985; A61K31/501; A61K31/5025; A61K31/506; A61K31/519; A61P1/04; A61P11/06; A61P19/02; A61P29/00; A61P37/06; A61P37/08; C07D401/04; C07D405/04; C07D409/04; C07D413/04; C07D417/04; C07D471/04; C07D487/04; C07D491/048; C07D495/04; C07D519/00