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Title:
β-GLUCURONIDASE INHIBITOR
Document Type and Number:
Japanese Patent JP2006045188
Kind Code:
A
Abstract:

To obtain a β-glucuronidase inhibitor that is safe and hence applicable to foods and cosmetics.

This β-glucuronidase inhibitor contains, as an active ingredient, fluorotannin or a seaweed or an extract of a seaweed selected from the group consisting of Laminaria japonica, Eisenia bicyclis, Eisenia arborea, Ecklonia stlonifera, Ecklonia kurome, Ecklonia cava, Undaria pinnatifida, Undaria peterseniana, Undaria undarioides, Alaria praelomga and Alaria crassifolia; Sargassum fuluvellum, Hizikia fusiforme and Sargassum horneri; Nemacystus decipieus and Cladosiphon okamuranus; and a seaweed belonging to red algae, the genus Gigartina tenella, the order Gigartinaceae.


Inventors:
MIYAZAKI TOSHITSUGU
ITO HISATOMI
SHIOJIRI MASATOSHI
Application Number:
JP2005041706A
Publication Date:
February 16, 2006
Filing Date:
February 18, 2005
Export Citation:
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Assignee:
NAGASE & CO LTD
International Classes:
A61K36/02; A23L1/30; A61K8/96; A61P43/00; C12N9/99
Domestic Patent References:
JPS63218611A1988-09-12
JP2002255776A2002-09-11
JPH02245087A1990-09-28
JP2002212095A2002-07-31
JP2003277203A2003-10-02
JP2004189648A2004-07-08
Other References:
DAVID M. WHITAKER ET AL.: "Anti-Inflammation mechanism of extract from Eisenia bicyclis (Kjellman) setchell", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 64, no. 7, JPN6009025258, July 1975 (1975-07-01), pages 1258 - 1259, ISSN: 0001330382
FISHERIES SCIENCE, vol. 62, no. 6, JPN6007015174, 1996, pages 923 - 926, ISSN: 0001330388
DAVID M. WHITAKER ET AL.: "Pharmacological evaluation of an extract from Eisenia bicyclis", FOOD-DRUGS FROM THE SEA PROCEEDINGS 1972, JPN6009025260, 1972, pages 97 - 103, ISSN: 0001330383
MONTSERRAT GUDIEL-URBANO ET AL.: "Effect of edible seaweeds (Undaria pinnatifida and Porphyra ternera) on the metabolic activities of", NUTRITION RESEARCH, vol. 22, no. 3, JPN6009025264, March 2002 (2002-03-01), pages 323 - 331, ISSN: 0001330384
SEKIKAWA C ET AL.: "Inhibition of β-Glucuronidase by Extracts of Chondria crassicaulis.", 北海道大学水産科学研究い報, vol. 53, no. 1, JPN6009025261, 27 March 2002 (2002-03-27), pages 27 - 30, ISSN: 0001330385
関川千里 他: "海藻のβ-グルクロニダーゼ阻害成分のスクリーニングと精製", 日本水産学会北海道支部大会講演要旨集, vol. 1999, JPN6009025262, 4 December 1999 (1999-12-04), pages 25 - 219, ISSN: 0001330386
関川千里 他: "スジメに含まれるβ-グルクロニダーゼ阻害活性成分", 日本水産学会北海道支部大会講演要旨集, vol. 2002, JPN6009025263, 29 November 2002 (2002-11-29), pages 37, ISSN: 0001330387
Attorney, Agent or Firm:
Hiromichi Nanjo