Title:
シュードモナス由来のPA-ILレクチン、PA-IILレクチンまたは両方のレクチンのグリコミメティック阻害剤
Document Type and Number:
Japanese Patent JP5175190
Kind Code:
B2
Abstract:
Compositions and methods are provided related to Pseudomonas bacteria. The compositions and methods may be used for diagnosis and therapy of medical conditions involving infection with Pseudomonas bacteria. Such infections include Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis. A compound useful in the present methods may be used in combination with a therapeutic agent or may be linked to a therapeutic agent. Pseudomonas bacteria may be inhibited by blocking colonization, inhibiting virulence factors, arresting growth or killing the bacteria.
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Inventors:
Magnani, John El.
Patton, John Tea. Junior
Sarkar, Arun Khe.
Patton, John Tea. Junior
Sarkar, Arun Khe.
Application Number:
JP2008526154A
Publication Date:
April 03, 2013
Filing Date:
August 08, 2006
Export Citation:
Assignee:
Glycomimetics, Incorporated
International Classes:
C07H17/04; A61K31/7048; A61K45/00; A61P31/04; A61P43/00; C12N11/02; C12Q1/04; G01N33/569
Foreign References:
| WO2004058304A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita