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Title:
グランザイムBを指向するイメージングおよび治療
Document Type and Number:
Japanese Patent JP7194595
Kind Code:
B2
Abstract:
Provided herein are compounds useful for imaging granzyme B. An exemplary compound provided herein is useful as a radiotracer for position emission tomography (PET) and/or single photon emission tomography (SPECT) imaging. Methods of imaging granzyme B, combination therapies, and kits comprising the granzyme B imaging agents are also provided.

Inventors:
Mahmood, Umar
Larimar, Benjamin
Wellenberg-Klee, Eric
Application Number:
JP2018568685A
Publication Date:
December 22, 2022
Filing Date:
June 30, 2017
Export Citation:
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Assignee:
The General Hospital Corporation
International Classes:
C07K7/06; A61K47/54; A61K47/62; A61K49/00; A61K51/08; C07K7/08; G01N33/573
Domestic Patent References:
JP2012513591A
Foreign References:
KR1020140119633A
US20070184493
Other References:
Circ. Res. (2015) vol.117, issue 6, p.502-512
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Ueda Wataru