Title:
グアニジニウム官能化オリゴマーとその製造法
Document Type and Number:
Japanese Patent JP2004500330
Kind Code:
A
Abstract:
The present invention provides oligomers which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the nucleoside moieties of the oligomer is modified to include a guanidinium group. These oligomers are useful for diagnostic, therapeutic and investigative purposes.
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Inventors:
Manoharan, Mutia
Cook, Philip Dunn
Prakash, Tarza Pea
Mohan, Benkatraman
Cook, Philip Dunn
Prakash, Tarza Pea
Mohan, Benkatraman
Application Number:
JP2001507859A
Publication Date:
January 08, 2004
Filing Date:
July 07, 2000
Export Citation:
Assignee:
Isis PharmaceuticalsInc
International Classes:
C07H21/02; A61K31/712; A61K48/00; A61P35/00; C07C335/38; C07F9/24; C07H21/00; C07H21/04; (IPC1-7): C07H21/02; A61K31/712; A61K48/00; A61P35/00; C07C335/38; C07F9/24; C07H21/04
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takashi Nakata
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takashi Nakata