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Title:
腸内細菌叢改善組成物
Document Type and Number:
Japanese Patent JP6917662
Kind Code:
B2
Abstract:
It is an object of the present invention to provide a composition for improving intestinal flora.The composition for improving intestinal flora includes gnetin C and/or a glycoside thereof for proliferating Akkermansia having an effect of improving the intestinal flora.

Inventors:
Mitsuhiro Watanabe
Shotaro Hosoda
Application Number:
JP2020551115A
Publication Date:
August 11, 2021
Filing Date:
October 04, 2019
Export Citation:
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Assignee:
Hosoda shc Co., Ltd.
International Classes:
A61K31/343; A23L2/52; A23L33/105; A61K36/13; A61P1/04; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P35/00
Domestic Patent References:
JP6362237B2
Other References:
YONESHIRO, T. et al.,Melinjo (Gnetum gnemon L.) seed extract induces uncoupling protein 1 expression in brown fat and protects mice against diet-induced obesity, inflammation, and insulin resistance,Nutrition research,2018年 7月 3日,Vol.58,pp.17-25
NARAYANAN, N.K. et al.,Antitumor activity of melinjo (Gnetum gnemon L.) seed extract in human and murine tumor models in vitro and in a colon-26 tumor-bearing mouse model in vivo,Cancer medicine,2015年,Vol.4, No.11,pp.1767-1780
高科庸子ほか,グネチンC(レスベラトロール二量体)の薬効効果,第16回 日本抗加齢医学会総会 プログラム・抄録集,2016年,p.200 [P03]
加藤榮信ほか,メリンジョ成分の生物作用,日本健康医学会雑誌,2007年,Vol.16, No.3,pp.74-75
山口佳之ほか,FOCUS 免疫チェックポイント(PD-1/PD-L1)がもたらしたがん治療のパラダイムシフト,臨床外科,2017年,Vol.72, No.7,pp.876-880
Attorney, Agent or Firm:
Tomoko Tsujida
Daisuke Muramatsu