HIV replication inhibitor

Japanese Patent JP6281952

B2

The present invention provides a novel compound having an antiviral activity, in particular, an HIV replication inhibiting activity, as well as a pharmaceutical composition, in particular, an anti-HIV agent. wherein ring A is substituted or unsubstituted carbocycle or substituted or unsubstituted heterocycle; R 1 is substituted or unsubstituted alkyl etc.; R 2 is substituted or unsubstituted alkyloxy etc.; n is 1 or 2; R 3 is substituted or unsubstituted carbocyclyl or substituted or unsubstituted heterocyclyl; R 4 is a hydrogen atom etc.; R 6 is substituted or unsubstituted alkyl etc.

Kenji Tomita
Yoshiyuki Amada
Iwaya Tsutomu
Takashi Kawasuji
Akiyama Toshiyuki
Shuichi Sugiyama
Yoshinori Tamura
Ritsu Iwazu

JP2014559726A

February 21, 2018

January 30, 2014

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Shionogi Pharmaceutical Co., Ltd.

C07D209/58; A61K31/352; A61K31/382; A61K31/395; A61K31/403; A61K31/4184; A61K31/433; A61K31/4439; A61K31/473; A61K31/4741; A61K31/4743; A61K31/4745; A61K31/498; A61K31/4985; A61K31/499; A61K31/502; A61K31/517; A61K31/538; A61K31/5383; A61K31/5386; A61K31/5415; A61K31/549; A61K31/55; A61K31/551; A61K31/5513; A61K31/553; A61K31/554; A61P31/18; A61P43/00; C07D209/80; C07D209/86; C07D209/88; C07D221/12; C07D221/16; C07D221/18; C07D223/18; C07D225/08; C07D237/26; C07D241/44; C07D243/04; C07D243/12; C07D243/14; C07D265/34; C07D267/00; C07D267/18; C07D267/20; C07D267/22; C07D279/02; C07D281/02; C07D281/18; C07D285/36; C07D291/08; C07D311/80; C07D335/10; C07D401/04; C07D405/04; C07D405/14; C07D409/04; C07D413/04; C07D417/04; C07D471/04; C07D471/06; C07D471/10; C07D487/04; C07D491/048; C07D491/056; C07D491/06; C07D491/107; C07D495/04; C07D495/14; C07D498/04; C07D513/04; C07D513/06; C07D519/00

JP2012526728A

EP2511273A1
WO2012003497A1

Hideaki Yamauchi
Kenichi Sugita
Hiromitsu Takayama

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