Title:
HIV治療
Document Type and Number:
Japanese Patent JP2005521393
Kind Code:
A
Abstract:
The present invention provides siRNA methods and compositions for inhibiting HIV infection and/or replication, as well as systems for identifying effective siRNAs for inhibiting HIV and systems for studying HIV infective mechanisms. The invention also provides methods and compositions for inhibiting infection, pathogenicity and/or replication of an infectious agent; for example, by using siRNAs to inhibit host cell gene expression.
Inventors:
Beresford, Paul Jay.
Lieberman, Judy
Murray, Michael F.
Novina, Karl Dee.
Sharp, Philip A.
Lieberman, Judy
Murray, Michael F.
Novina, Karl Dee.
Sharp, Philip A.
Application Number:
JP2003577602A
Publication Date:
July 21, 2005
Filing Date:
March 20, 2003
Export Citation:
Assignee:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
The Center for Blood Research, Inc.
Briham and Wimins Hospital, Incorporated
The Center for Blood Research, Inc.
Briham and Wimins Hospital, Incorporated
International Classes:
A61K31/7105; A61K31/711; A61K35/12; A61K35/76; A61K48/00; A61P31/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N5/22; A01K67/027; C12N15/09; C12N15/113; C12N15/48; A61K38/00; C12Q1/70; (IPC1-7): C12N15/09; A01K67/027; A61K31/7105; A61K31/711; A61K35/12; A61K35/76; A61K48/00; A61P31/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita