PURPOSE: To obtain a hair-growth and hair-tonic agent effective in preventing and ameliorating premature alopecia caused by excessive secretion of male hormone, by compounding a β-D-glucuronidase inhibitor.

CONSTITUTION: A hair-growth and hair-tonic agent compounded with β-D- glucuronidase. Testosterone glucuronide in blood is decomposed in a target organ with β-D-glucuronidase and is taken into a cell to cause premature alopecia. The present hair-growth and hair-tonic agent is designed to inhibit the action of glucuronidase by the use of a competitive inhibitor of glucuronidase. It is a safe cosmetic usable without causing any adverse effect on scalp, etc., during use.