Title:
HALOACETYLUREA DERIVATIVE
Document Type and Number:
Japanese Patent JPS62149655
Kind Code:
A
Abstract:
NEW MATERIAL:A compound shown by formula I [A is group shown by formula II W formula IV (R1 is H, alkyl, phenyl, etc.; R2 is alkyl; R3 is H, alkyl etc.; R4 and R5 are H or methyl; n is 0 or 1; Y1 and Y2 are H or alkyl); R is H, alkyl or 1-alkoxycarbonylethyl; X is halogen].
EXAMPLE: 1-Chloroacetyl-3-(3-trifluoromethyl-5-isoxazolyl)urea.
USE: A medical antifungal agent or an agricultural fungicide.
PREPARATION: An amine shown by the formula A-NHR is reacted with chloroacetyl isocyanate shown by the formula OCN-COCH2Cl in a solvent such as benzene, etc., at 50W130°C to give a compound shown by formula I.
Inventors:
SUMIMOTO SHINZABURO
ISHIZUKA ICHIRO
UEDA SHIRO
TAKASE AKIRA
TAWARA KATSUYA
ISHIZUKA ICHIRO
UEDA SHIRO
TAKASE AKIRA
TAWARA KATSUYA
Application Number:
JP29660785A
Publication Date:
July 03, 1987
Filing Date:
December 24, 1985
Export Citation:
Assignee:
SHIONOGI & CO
International Classes:
A61K31/17; A61K31/42; A61P31/04; C07C67/00; C07C239/00; C07C275/50; C07D261/04; C07D261/14; (IPC1-7): A61K31/17; A61K31/42; C07C127/22; C07D261/04; C07D261/14
Attorney, Agent or Firm:
Mitsutaka Iwasaki