HAPTEN DERIVATIVE, ITS PREPARATION, HAPTEN/PROTEIN CONJUGANT, ITS PREPARATION, PREPARATION OF ANTIBODY, AND LABELED ENZYME FOR IMMUNOASSAY

Title:

HAPTEN DERIVATIVE, ITS PREPARATION, HAPTEN/PROTEIN CONJUGANT, ITS PREPARATION, PREPARATION OF ANTIBODY, AND LABELED ENZYME FOR IMMUNOASSAY

Document Type and Number:

Japanese Patent JPH02138293

Kind Code:

A

Abstract:

NEW MATERIAL: A compound of formula I (Hap is a residue formed by eliminating oxo group from hapten carrying a keto group or aldehyde group; R1 and R2 are 1-7C alkyl and either R1 or R2 is H).

USE: A hapten/protein conjugant, labeled enzyme for immunoassay.

PROCESS: Hapten is reacted with a compound of formula II, e.g. a corresponding hydrochloride or hydrobromine of carboxylalkoxyamine in alkaline conditions to convert the keto or aldehyde group into an oxime derivative.

Inventors:

ERASUMUSU FUUBAA
KURISUCHIYAN KURAIN
GUNTAA PATSUPERUTO
KURAUSU HARAAMAIYAA

Application Number:

JP1331589A

Publication Date:

May 28, 1990

Filing Date:

January 24, 1989

Export Citation:

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Assignee:

BOEHRINGER MANNHEIM GMBH

International Classes:

G01N33/53; A61K39/385; C07H15/26; C07J1/00; C07J41/00; C07J43/00; C07K14/00; C12P21/08; G01N33/531; G01N33/532; G01N33/535; G01N33/543; G01N33/74; G01N33/94; (IPC1-7): A61K39/385; C07J1/00; C07K3/08; C07K15/12; C07K15/16; C12P21/08; G01N33/53; G01N33/531; G01N33/535

Attorney, Agent or Firm:

Toshio Yano (1 outside)

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