Title:
HDAC6 INHIBITORS AND IMAGING AGENTS
Document Type and Number:
Japanese Patent JP2023025088
Kind Code:
A
Abstract:
To provide radiolabeled compounds useful as a radiotracer for positron emission tomography imaging of HDAC, and provide methods for preparing unlabeled and labeled compounds, diagnostic methods, and methods of treating diseases associated with HDAC.SOLUTION: The present invention encompasses a compound useful for binding to one or more histone deacetylase enzymes (HDACs), represented by the following formula I.SELECTED DRAWING: None
Inventors:
Rocca, Johanna Carlina
Hooker, jacob
One, Changnin
Strible-Bantillo, Martin Georg
Hooker, jacob
One, Changnin
Strible-Bantillo, Martin Georg
Application Number:
JP2022186399A
Publication Date:
February 21, 2023
Filing Date:
November 22, 2022
Export Citation:
Assignee:
The General Hospital Corporation
International Classes:
C07C259/10; A61K31/166; A61K31/44; A61K51/00; A61P25/00; A61P25/14; A61P25/18; A61P25/24; A61P25/28; A61P29/00; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07D213/81
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Sayaka Hirakawa
Norio Omori
Sayaka Hirakawa