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Title:
ヘリコバクター・ピロリと大腸菌O157:H7に対する抗菌性に優れたラクトバシラスパラカゼイ亜種パラカゼイ
Document Type and Number:
Japanese Patent JP4261185
Kind Code:
B2
Abstract:
The present invention relates to novel lactic microorganism, method for preparation and uses thereof. Particularly, the present invention relates to novel Lactobacillus paracasei strain (Lactobacillus paracasei subsp. paracasei CSK 01) which is prepared by the process comprising the steps: (1) administering lactic bacteria derived from gastric mucus of pig to patients of gastritis and enteritis; (2) separating lactic bacteria from the patients' feces again after their complete recovery; and (3) identifying the bacteria strain by performing 16S rRNA sequencing and RAPD polymerase chain reaction. The Lactobacillus strain of the present invention can attach to and proliferate on gastric and intestinal mucosa, resist to acidic and bilious conditions outstandingly and have excellent antibacterial properties. Therefore, the Lactobacillus strain and its antibacterial substance can be utilized widely to develop new drugs, functional food, health promoting additives and the like.

Inventors:
CHO Seong-kun
Application Number:
JP2002555217A
Publication Date:
April 30, 2009
Filing Date:
December 28, 2001
Export Citation:
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Assignee:
CHO Seong-kun
International Classes:
A23L1/30; C12N1/20; A23C9/123; A23L29/00; A61K35/74; A61P1/04; A61P31/04; C07G11/00; C12N1/02; C12N1/21; C12Q1/04; C12Q1/68; C12R1/245
Domestic Patent References:
JP2089625A
Other References:
DDBJ/EMBL/GenBank data base,1997年 2月18日,Accession No. D86517
Int.J.Sys.Bacteriol.,,1997年 1月,Vol.47, No.1,p.54-57
食品と開発,1999年,Vol.34, No.2,p.15-17
Attorney, Agent or Firm:
▲吉▼川 俊雄