Title:
５，１０－メチレン－（６Ｒ）－テトラヒドロ葉酸のヘミ硫酸塩
Document Type and Number:
Japanese Patent JP7396960
Kind Code:
B2
Abstract:
The present invention is directed towards the hemisulfate salt of 5,10-methylene-(6R)-tetrahydrofolic acid, preferably in substantially crystalline form, as well as pharmaceutical compositions and uses thereof in therapy, preferably chemotherapy.
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Inventors:
Moser Rudolph
Grain viola
Egger Thomas
Aman Thomas
Grain viola
Egger Thomas
Aman Thomas
Application Number:
JP2020083208A
Publication Date:
December 12, 2023
Filing Date:
May 11, 2020
Export Citation:
Assignee:
Merck & Company
International Classes:
C07D475/04; A61K9/19; A61K31/519; A61P35/00
Domestic Patent References:
| JP2009514776A | ||||
| JP5294968A | ||||
| JP718084A | ||||
| JP2009518305A | ||||
| JP2005524655A |
Attorney, Agent or Firm:
Mitsufumi Ezaki
Blacksmith Minoru Sawa
Katsuri Uenishi
Ichiro Torayama
Blacksmith Minoru Sawa
Katsuri Uenishi
Ichiro Torayama
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