PURPOSE: To sustain an adsorbing function for a long time and to obtain a firm coupling by allowing an egg antibody against free hemoglobin to coexist on an insoluble carrier through the intermediary of a spacer.
CONSTITUTION: An egg anti-body against free hemoglobin is fixed to an insoluble solid body so as to be allowed to coexist thereon through the intermediary of a spacer (polyalkylene oxide having a polymerization degree of 5 to 500) so as to remove or trap free hemoglobin in the entire blood or in the blood plasma. As the spacer, a chemical compound expressed by formula I may be used where (n) is an integer from 0 to 10, (m) is an integer from 5 to 300 and I is 1 or 2, R1 and R2 are hydrogen atoms or a methyl group same or different from each other. Micropores are preferably presented on the outer surface of the carrier in order to enhance the effective area thereof.
Kazunori Inamori
Hideyuki Yokota
Masakazu Tanaka
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