単純ヘルペス1型ウイルス欠失変異型およびそのワクチン - The University Court Of The University Of Glasgow

Title:

単純ヘルペス1型ウイルス欠失変異型およびそのワクチン

Document Type and Number:

Japanese Patent JP4195080

Kind Code:

B2

Abstract:

Novel Herpes simplex viruses and vaccines based on such novel HSV-1 strains are described. In particular, viruses having a deletion in the terminal portion of RL are provided. The virus can be further modified to express heterologous antigens and also engineered to overproduce HSV Light particles. This is achieved by incorporating a ts mutation into the UL26 gene.

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Inventors:

Brown, Susan Moira
McLean, Arsdeia Rodarick

Application Number:

JP50358292A

Publication Date:

December 10, 2008

Filing Date:

January 30, 1992

Export Citation:

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Assignee:

The University Court Of The University Of Glasgow

International Classes:

C12N7/00; A61K39/245; A61P31/12; A61P31/22; C12N7/01; C12N7/04; C12N15/09

Other References:

Science,(1990)Vol.250, p.1262-1266
J.Gen.Virol., (1989)Vol.70, p.705-716
Virology, (1989)Vol.172, p.435-450

Attorney, Agent or Firm:

Aoyama Aoi
Mitsuo Tanaka

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