Title:
HETEROCYCLIC COMPOUND, MANUFACTURE AND MEDICINAL COMPOSITION HAVING CARDIAC STIMULANT AND/OR ANTIHYPERTENSIVE ACTIVITY
Document Type and Number:
Japanese Patent JPS58131981
Kind Code:
A
Abstract:
Heterocyclic compounds of the formula: wherein A is a direct link, or is alkylene of 1 to 4 carbon atoms or alkenylene of 2 to 4 carbon atoms; wherein either X is -CR1R2- and Y is -O-, -S- or -NR3-, wherein R1, R2 and R3, which may be the same or different, each is hydrogen or alkyl of up to 4 carbon atoms; or X is -O-, -S- or -NH- and Y is -CR1R2- wherein R1 and R2 have the meanings stated above; and wherein Het is a 5- or 6-membered heterocyclic ring containing 1, 2 or 3 heteroatoms selected from nitrogen, oxygen or sulphur atoms, which ring may be unsubstituted or may bear one or two substituents as set out in claim 1, provided that when X is -CR1R2- and A is a direct link, Het is not unsubstituted 2-furyl; and salts thereof where appropriate; processes for their manufacture and pharmaceutical compositions containing them. The compounds possess cardiotonic and/or antihypertensive activity.
Inventors:
RODONII BURAIAN HAAGURIIBUSU
BAANAADO JIYOZEFU MAKUROORIN
SUTEYUAATO DENETSUTO MIRUZU
BAANAADO JIYOZEFU MAKUROORIN
SUTEYUAATO DENETSUTO MIRUZU
Application Number:
JP19784282A
Publication Date:
August 06, 1983
Filing Date:
November 12, 1982
Export Citation:
Assignee:
ICI LTD
International Classes:
A61K31/53; A61K31/535; A61K31/54; A61P9/04; A61P9/12; A61P37/04; C07D213/40; C07D213/61; C07D213/81; C07D213/83; C07D215/48; C07D253/06; C07D273/04; C07D285/16; C07D307/68; C07D307/81; C07D333/24; C07D333/28; C07D333/38; C07D333/58; C07D333/68; C07D401/04; C07D405/04; C07D409/04; C07D409/06; C07D413/04; C07D413/06; C07D417/04; (IPC1-7): C07D401/04; A61K31/53; A61K31/535; A61K31/54; C07D405/04; C07D409/04; C07D413/04; C07D417/04
Attorney, Agent or Firm:
Toshio Yano