MK2阻害剤として有用なヘテロ環式化合物

Title:

MK2阻害剤として有用なヘテロ環式化合物

Document Type and Number:

Japanese Patent JP2010533674

Kind Code:

A

Abstract:

The present invention describes tetracyclic compounds of formula (IA) or (IB), wherein the symbols R, X, A, Y, R2, R3 and D are as defined in the specification, their use in the treatment of certain diseases, e.g. depending on MK-2 or TNF activity, and ways of manufacturing them.

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Inventors:

Achim Schlapbach
Larszlo Lewes
Guido Koch

Application Number:

JP2010516479A

Publication Date:

October 28, 2010

Filing Date:

July 14, 2008

Export Citation:

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Assignee:

Novartis Age

International Classes:

C07D471/20; A61K31/438; A61K31/444; A61K31/499; A61K31/519; A61K31/527; A61K31/5377; A61K45/00; A61P1/02; A61P1/04; A61P1/18; A61P3/00; A61P5/00; A61P7/00; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P15/00; A61P17/00; A61P17/02; A61P17/06; A61P19/00; A61P19/02; A61P19/04; A61P19/06; A61P19/08; A61P21/00; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/18; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D471/14; C07D491/20

Attorney, Agent or Firm:

Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa
Yasushi Ochiai

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