Title:
ALK阻害剤としての複素環式誘導体
Document Type and Number:
Japanese Patent JP2013525476
Kind Code:
A
Abstract:
The invention relates to compounds of Formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases in which ALK protein is involved or in which inhibition of ALK activity may induce benefit, especially for the treatment of cancer mediated by a mutated EML4-ALK fusion protein.
Inventors:
Mark edward banage
Andrew Simon Cook
Jinron Gene Kui
Kevin Nail Duck
Judith Gale Deal
Dunling
Min In Hee
Patrick Stefan Johnson
Ted William Johnson
Fonty cucumber
Cynthia Louise Palmer
Hong Shen
Andrew Simon Cook
Jinron Gene Kui
Kevin Nail Duck
Judith Gale Deal
Dunling
Min In Hee
Patrick Stefan Johnson
Ted William Johnson
Fonty cucumber
Cynthia Louise Palmer
Hong Shen
Application Number:
JP2013508608A
Publication Date:
June 20, 2013
Filing Date:
May 04, 2011
Export Citation:
Assignee:
Pfizer Inc.
International Classes:
C07D213/73; A61K31/4418; A61K31/4439; A61K31/444; A61K31/4545; A61K31/46; A61K31/496; A61K31/497; A61K31/501; A61K31/506; A61K31/5365; A61K31/5377; A61K31/66; A61P35/00; A61P35/02; A61P43/00; C07D241/20; C07D401/04; C07D401/12; C07D401/14; C07D403/04; C07D403/14; C07D409/14; C07D413/04; C07D413/14; C07D417/04; C07D417/14; C07D451/04; C07D471/04; C07D498/04; C07F9/6518
Domestic Patent References:
| JP2008510788A | 2008-04-10 | |||
| JP2006519232A | 2006-08-24 | |||
| JP2008510790A | 2008-04-10 | |||
| JP2008510792A | 2008-04-10 |
Foreign References:
| WO2008088881A1 | 2008-07-24 | |||
| WO2012116050A2 | 2012-08-30 | |||
| WO2008053157A1 | 2008-05-08 | |||
| WO2009100282A1 | 2009-08-13 |
Attorney, Agent or Firm:
Noh four
High Hoji Koji
Junko Miyazawa
Maki Sato
Tatsuta Miyuki
High Hoji Koji
Junko Miyazawa
Maki Sato
Tatsuta Miyuki