Title:
高濃度抗体含有溶液製剤
Document Type and Number:
Japanese Patent JP4937358
Kind Code:
B2
Abstract:
The problem to be solved is to provide an antibody-containing formulation which is stable and suited for subcutaneous administration, wherein dimerization and deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and methionine.
Inventors:
Morishiki Toshiyuki
Daisuke Kameoka
Yoshimi Imaeda
Tereda Maeda
Staohie, Oliver Boris
Daisuke Kameoka
Yoshimi Imaeda
Tereda Maeda
Staohie, Oliver Boris
Application Number:
JP2009548102A
Publication Date:
May 23, 2012
Filing Date:
December 26, 2008
Export Citation:
Assignee:
Chugai Pharmaceutical Co., Ltd.
International Classes:
A61K39/395; A61K9/08; A61K47/18; A61P43/00
Domestic Patent References:
| JP2005527503A | 2005-09-15 | |||
| JP2007511566A | 2007-05-10 | |||
| JP2007204498A | 2007-08-16 |
Foreign References:
| WO2002013860A1 | 2002-02-21 |
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Akiko Nakahama
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Akiko Nakahama