Title:
銅塩を用いるアミド化合物の高選択的O-アルキル化方法
Document Type and Number:
Japanese Patent JP4345095
Kind Code:
B2
Abstract:
Compounds having one or more structures represented by general formula (I) as partial structure thereof, which are typified by pyrimidone and pyridone compounds, have two or more reaction sites in alkylation reactions. Accordingly, there is no process for producing O-alkylated products of these compounds at a high selectivity or such processes, if any, are applicable exclusively to those having limited structures. A process for selectivity O-alkylating such a compound as described above by converting it into the copper salt by using a monovalent copper compound such as copper suboxide and then reacting it with an alkylating agent having a leaving group in the presence of a phosphorus compound such as a phosphite. Pyrimidyloxy derivatives or pyridyloxy derivatives obtained by this reaction is useful as intermediates of pesticides or drugs.
Inventors:
Takase Mitsuru
Miyazawa Yasuyuki
Shiro Tsubokura
Miyazawa Yasuyuki
Shiro Tsubokura
Application Number:
JP2000534519A
Publication Date:
October 14, 2009
Filing Date:
March 04, 1999
Export Citation:
Assignee:
Nippon Soda Co., Ltd.
International Classes:
C07B41/04; B01J23/72; B01J27/228; C07D239/52
Domestic Patent References:
| JP5279330A | ||||
| JP63216848A |
Foreign References:
| WO1997001538A1 |
Attorney, Agent or Firm:
Yasunori Matsuhashi