Title:
ヒストンデアセチラーゼインヒビター
Document Type and Number:
Japanese Patent JP2006520796
Kind Code:
A
Abstract:
Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
Inventors:
Breathy Jerome
Brown Jason W
Khao Sheldon X
Ganggrove anthony are
Jennings Andrew Jay
Stafford Jeffrey A
Vue von H
Xiao Xiao Yi
Brown Jason W
Khao Sheldon X
Ganggrove anthony are
Jennings Andrew Jay
Stafford Jeffrey A
Vue von H
Xiao Xiao Yi
Application Number:
JP2006507336A
Publication Date:
September 14, 2006
Filing Date:
March 17, 2004
Export Citation:
Assignee:
Takeda San Diego Inc.
International Classes:
C07D235/18; A61K31/4184; A61K31/454; A61K31/519; A61K31/52; A61K31/53; A61K31/535; A61P1/04; A61P9/10; A61P9/14; A61P15/00; A61P17/02; A61P17/06; A61P19/02; A61P27/02; A61P27/06; A61P29/00; A61P31/04; A61P31/22; A61P33/00; A61P33/02; A61P35/00; A61P35/02; A61P35/04; A61P41/00; A61P43/00; C07D401/04; C07D401/06; C07D401/14; C07D403/06; C07D403/10; C07D413/02; C07D417/02; C07D453/02; C07D471/04; A61K31/439; A61K31/4439; A61K31/4545; A61K31/5377; C12N9/99; A61K
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama