ヒストンデアセチラーゼ阻害薬及び組成物並びにそれらの使用の方法

Japanese Patent JP6600319

B2

Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.

JPS59175456	N-ALKENYL-N-ACYLHYDROXYLAMINE DERIVATIVE, ITS PREPARATION AND ITS USE
JPH093031	HYDROXAMIC ACID DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE CONTAINING THE SAME
JP2002080446	NEW COMPOUND F-15603 AND METHOD FOR PRODUCING THE SAME

Dominguez, Ceria
Mnotu-San Juan, Ignacio
Luckhurst, Christopher, A.
Allen, Daniel, Earl.
Ruffy, Gilles
Bari, Roland, W.
Brescia, Parra
Hougan, Alan, F.
Wishart, Grant
Hyges, Samantha, Jay.
Jarvis, Rebecca, Yi.
Vetera, Who, Dee.
Penrose, Stefan, Dee.
Wall, michael
Stott, Andrew, Jay.
Savile-Stones, Elizabeth

JP2016570849A

October 30, 2019

June 01, 2015

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CHD Foundation, Incorporated

C07C259/08; A61K31/16; A61K31/416; A61K31/428; A61K31/4439; A61K31/497; A61K31/506; A61K31/517; A61P25/14; C07D231/54; C07D231/56; C07D239/70; C07D239/74; C07D239/88; C07D275/04; C07D277/60; C07D277/62; C07D277/66; C07D277/82; C07D401/04; C07D417/04

JP2010523601A
JP2010540630A
JP2008540623A
JP2007508318A

WO2012012320A1
WO2011106632A1
WO2012152208A1

Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Atsushi Ohara

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