Title:
HISTOTRIPSY EXCITATION SEQUENCE OPTIMIZED FOR BUBBLE CLOUD FORMATION USING SHOCK SCATTERING
Document Type and Number:
Japanese Patent JP2022017543
Kind Code:
A
Abstract:
To provide methods and devices for producing cavitation in tissue.SOLUTION: In one embodiment, a shock scattering method of Histotripsy therapy comprises delivering an initiation pressure waveform from an ultrasound therapy transducer into tissue, the initiation pressure waveform being configured to produce at least one bubble in the tissue, delivering a scattering pressure waveform from the ultrasound therapy transducer into the at least one bubble within a life-cycle of the at least one bubble, and producing cavitation nuclei near the at least one bubble with the scattering pressure waveform. The scattering pressure waveform can be delivered during the life-cycle of the at least one bubble. In some embodiments, the scattering pressure waveform is delivered within 5 μs to 1 s of the initiation pressure waveform. Systems for performing shock scattering Histotripsy therapy are also discussed.SELECTED DRAWING: Figure 1
Inventors:
JONATHAN CANNATA
TIMOTHY L HALL
ADAM MAXWELL
DEJAN TEOFILOVIC
TIMOTHY L HALL
ADAM MAXWELL
DEJAN TEOFILOVIC
Application Number:
JP2021182948A
Publication Date:
January 25, 2022
Filing Date:
November 10, 2021
Export Citation:
Assignee:
HISTOSONICS INC
UNIV MICHIGAN
UNIV MICHIGAN
International Classes:
A61N7/00
Attorney, Agent or Firm:
Osamu Yamamoto
Toru Miyamae
Tatsumi Ono
Toru Miyamae
Tatsumi Ono
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