Title:
チオレドキシン発現に基づいた化学療法後の非小細胞肺癌の無進行期間の決定方法
Document Type and Number:
Japanese Patent JP2010526996
Kind Code:
A
Abstract:
The present invention relates to a method for predicting the Time to Progression (TTP) of non small cell lung carcinoma (NSCLC) patients treated with chemotherapy, based on the detecting the levels of expression of thioredoxin (TRX) in a biological sample of the patient, or based on simultaneously detecting the expression levels of thioredoxin and the methylation status of the 14-3-3Ã gene.
Inventors:
Rafael, Rossell, Costa
Miguel, Talon, Roca
Miguel, Talon, Roca
Application Number:
JP2010506946A
Publication Date:
August 05, 2010
Filing Date:
May 09, 2008
Export Citation:
Assignee:
PANGAEA BIOTECH, S.A.
International Classes:
G01N33/68; A61K31/282; A61K33/24; A61P35/00; C12Q1/68; G01N33/50; G01N33/53; C12N15/113
Attorney, Agent or Firm:
Kenji Yoshitake
Hirohito Katsunuma
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Hiroyuki Fujii
Hirohito Katsunuma
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Hiroyuki Fujii