Title:
効率的にターゲット分子を探索する方法
Document Type and Number:
Japanese Patent JP4907514
Kind Code:
B2
Abstract:
The present invention provides a solid phase carrier capable of adsorbing a highly hydrophobic target molecule, for example, a membrane associated protein, and a solid phase carrier optimized not only for a highly hydrophobic target molecule, but also for an optionally chosen target molecule. More specifically, the present invention provides a solid phase carrier having a ligand and a capping agent immobilized thereon, with the hydrophobic property of the surface thereof adjusted to enable the binding of the target molecule to the ligand, or to increase the amount of target molecule bound to the ligand; various methods using the solid phase carrier (for example, method of concentrating, isolating, or purifying a target molecule, a method of selectively adsorbing a particular target molecule to the solid phase carrier, or a method of analyzing the interaction between ligand and target molecule therefor); a production method for the solid phase carrier; and an improvement method for a solid phase carrier having a ligand and a capping agent immobilized thereon and the like.
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Inventors:
Akito Tanaka
Akira Yamazaki
Haramura Masayuki
Akira Yamazaki
Haramura Masayuki
Application Number:
JP2007500660A
Publication Date:
March 28, 2012
Filing Date:
January 26, 2006
Export Citation:
Assignee:
Reverse Proteomics Laboratory Inc.
International Classes:
G01N33/543; B01J20/24; B01J20/26; G01N33/53; G01N33/545; G01N33/566
Domestic Patent References:
| JP2004271514A | 2004-09-30 | |||
| JP2003329685A | 2003-11-19 | |||
| JP2005017233A | 2005-01-20 |
Foreign References:
| WO2004040305A1 | 2004-05-13 | |||
| WO2004025297A1 | 2004-03-25 |
Attorney, Agent or Firm:
Takashima Ichi