Title:
イリノテカンの製造方法
Document Type and Number:
Japanese Patent JP5863846
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a novel method for producing irinotecan using amines.SOLUTION: A method of producing irinotecan represented by the chemical formula (1) includes reacting 7-ethyl-10-hydroxycamptothecin with 1-chlorocarbonyl-4-piperidinopiperidine or hydrochloride thereof in the presence of a nonaromatic tertiary amine having 5 or less carbon atoms.
Inventors:
Choi, Yang Jae
Ji, Wankun
Kang, Suk Won
Ji, Wankun
Kang, Suk Won
Application Number:
JP2014024792A
Publication Date:
February 17, 2016
Filing Date:
February 12, 2014
Export Citation:
Assignee:
Jail Pharmaceutical Company Limited
International Classes:
C07D491/22
Domestic Patent References:
| JP2007161714A | ||||
| JP2008529992A | ||||
| JP2008529991A | ||||
| JP2008529993A | ||||
| JP2008509211A |
Attorney, Agent or Firm:
Takashima Ichi
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