Title:
特定の遺伝的特性を有する哺乳動物を作製する方法
Document Type and Number:
Japanese Patent JP4129472
Kind Code:
B2
Abstract:
Process for producing mammals with defined genetic properties, particularly transgenic mammals. Animals which are derived completely from ES cells are obtained by injecting totipotent cells (embryonic stem cells or embryonic germ cells) genetically manipulated and cultured in vitro into tetraploid blastocysts and implanting the resulting embryo in a foster mother, in a single operation.
Inventors:
Wagner Elwin
One Tsaoqui
One Tsaoqui
Application Number:
JP2006218386A
Publication Date:
August 06, 2008
Filing Date:
August 10, 2006
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
A01K67/027; C12N5/10; C12N15/00; C12N15/09; C12N5/00
Domestic Patent References:
| JP2000516463A |
Other References:
Theriogenology,1996年 3月,Vol. 45,833-842
Cell,1989年,Vol. 56,313-321
Exp. Anim.,1995年,Vol. 44,205-210
Nature,1992年,Vol. 360,741-745
Proc. Natl. Acad. Sci. USA,1993年,Vol. 90,8424-8428
Cell,1989年,Vol. 56,313-321
Exp. Anim.,1995年,Vol. 44,205-210
Nature,1992年,Vol. 360,741-745
Proc. Natl. Acad. Sci. USA,1993年,Vol. 90,8424-8428
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Shishido Kaichi
Nobuo Ogawa
Fumiaki Otsuka
Shishido Kaichi
Nobuo Ogawa