Title:
mRNAの安定化方法
Document Type and Number:
Japanese Patent JP5054025
Kind Code:
B2
Abstract:
A method to increase the production of a desired chemical compound in a microorganism by introduction of a DNA sequence at the 5′ end of the encoding DNA gene sequence capable of forming a stem loop and capable of increasing the stability of mRNA transcripts from one or more genes, thus stabilized mRNAs, corresponding DNA sequences and microorganisms.
Inventors:
Ferlandes, Abel
Perkins, John, Bee.
Charvel, michel
Perkins, John, Bee.
Charvel, michel
Application Number:
JP2008543705A
Publication Date:
October 24, 2012
Filing Date:
December 01, 2006
Export Citation:
Assignee:
DSM IP ASSETS B.V.
International Classes:
C12P1/04; C12N1/00; C12N15/09; C12P7/64; C12P13/04; C12P19/30; C12P21/00; C12P23/00; C12R1/125; (IPC1-7): F25B43/00; F25B39/02
Domestic Patent References:
| JP2002504379A |
Other References:
Microbiology, 149[3](2003) p.751-761
Mol. Microbiol., 32[6](1999) p.1183-1197
Metabol. Engineer. 3[4](2001) p.313-321
Mol. Microbiol., 32[6](1999) p.1183-1197
Metabol. Engineer. 3[4](2001) p.313-321
Attorney, Agent or Firm:
Yuichi Yamada
Masakazu Noda
Yoshinori Shimizu
Ikeda adult
Masakazu Noda
Yoshinori Shimizu
Ikeda adult