Title:
Foxp3+ナチュラルキラーT細胞および免疫関連疾患の治療方法
Document Type and Number:
Japanese Patent JP2012508575
Kind Code:
A
Abstract:
In one aspect, the invention provides isolated populations of cells comprising Foxp3+ natural killer T-cells, methods of generating Foxp3+ natural killer T-cells and methods for suppressing the immune response in specific organs, including the liver and the lungs.
Inventors:
Glasa, Luis Ricardo Simoes da Silva
Monteiro, Malta Sofia Ferreira
Monteiro, Malta Sofia Ferreira
Application Number:
JP2011536276A
Publication Date:
April 12, 2012
Filing Date:
November 13, 2009
Export Citation:
Assignee:
Institute de Medicina Molecular
Unibel Cidage De Lijuboa
Unibel Cidage De Lijuboa
International Classes:
C12N5/0783; A61K35/14; A61P37/06; A61P41/00; C12N15/09; A61K35/12; C07K14/54; C07K16/24
Domestic Patent References:
| JP2003530101A | 2003-10-14 |
Other References:
JOURNAL OF IMMUNOLOGY, vol. 169, no. 1, JPN6013029706, 2002, pages 31 - 38, ISSN: 0002560527
PNAS, vol. 98, no. 5, JPN6013029709, 2001, pages 2577 - 2581, ISSN: 0002560528
CLINICAL MEDICINE & RESEARCH, vol. 1, JPN6013029713, 2003, pages 13 - 20, ISSN: 0002560529
CELL, vol. 133, no. 5, JPN6013029715, May 2008 (2008-05-01), pages 775 - 787, ISSN: 0002560530
JOURNAL OF LEUKOCYTE BIOLOGY, vol. 81, JPN6013029718, 2006, pages 654 - 662, ISSN: 0002560531
DIABETES, vol. 57, no. 1, JPN6013029727, June 2008 (2008-06-01), pages 353 - 1239, ISSN: 0002560532
J. IMMUNOL., vol. 185, JPN6013029722, 2010, pages 2157 - 2163, ISSN: 0002560533
INT. IMMUNOL., vol. 23, no. 8, JPN6013029725, 2011, pages 473 - 484, ISSN: 0002560534
PNAS, vol. 98, no. 5, JPN6013029709, 2001, pages 2577 - 2581, ISSN: 0002560528
CLINICAL MEDICINE & RESEARCH, vol. 1, JPN6013029713, 2003, pages 13 - 20, ISSN: 0002560529
CELL, vol. 133, no. 5, JPN6013029715, May 2008 (2008-05-01), pages 775 - 787, ISSN: 0002560530
JOURNAL OF LEUKOCYTE BIOLOGY, vol. 81, JPN6013029718, 2006, pages 654 - 662, ISSN: 0002560531
DIABETES, vol. 57, no. 1, JPN6013029727, June 2008 (2008-06-01), pages 353 - 1239, ISSN: 0002560532
J. IMMUNOL., vol. 185, JPN6013029722, 2010, pages 2157 - 2163, ISSN: 0002560533
INT. IMMUNOL., vol. 23, no. 8, JPN6013029725, 2011, pages 473 - 484, ISSN: 0002560534
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Toshifumi Onuki