Title:
補体阻害剤による慢性障害の治療方法
Document Type and Number:
Japanese Patent JP6618682
Kind Code:
B2
Abstract:
In some aspects, the invention provides methods of treating a subject in need of treatment for a chronic complement-mediated disorder. In some aspects, the invention provides methods of treating a subject in need of treatment for a Th17-associated disorder. In some aspects, the invention provides methods of treating a subject in need of treatment for a chronic respiratory system disorder. In some aspects, the invention provides methods of administering a complement inhibitor to a subject. In some embodiments, a method of treating a subject comprises administering multiple doses of a complement inhibitor to the subject according to a dosing schedule that leverages the prolonged effect of complement inhibition in chronic respiratory disorders. In some embodiments, a subject has chronic obstructive pulmonary disease. In some embodiments, a subject has asthma.
Inventors:
Cedric Francois
Pascal DeChateletz
Pascal DeChateletz
Application Number:
JP2014517223A
Publication Date:
December 11, 2019
Filing Date:
June 22, 2012
Export Citation:
Assignee:
APELLIS PHARMACEUTICALS,INC.
International Classes:
A61K38/08; A61K9/72; A61P11/00; A61P11/06; A61P19/00; A61P21/00; A61P21/04
Domestic Patent References:
| JP2010540654A |
Other References:
Protein Sci.(1998)vol.7,no.3,p.619-627
Current Allergy and Asthma Reports(2011)Vol.11,No.2,p.122-130
Current Allergy and Asthma Reports(2011)Vol.11,No.2,p.122-130
Attorney, Agent or Firm:
Norihito Yamao
Yasushi Morimoto
Masahiro Nitta
Nobuhiko Akiyama
Yasushi Morimoto
Masahiro Nitta
Nobuhiko Akiyama