Title:
下痢の処置方法
Document Type and Number:
Japanese Patent JP4861500
Kind Code:
B2
Abstract:
A therapeutic method of treating diarrhea of a patient, such as that caused by rotavirus in which a liquid suspension of one or more strains of Lactobacillus reuteni is administered to the patient. Preferably the L. reuteri is isolated from an animal of the same species as the animal to which the therapy is being given. Preferably at least about 107 cells of L. reuteri, and most preferably, at least 108 cells, are administrated per day, over a period of one to seven days, depending on the severity of the gastroenteritis. The result is a rapid, dramatic reduction in animal's diarrhea and vomiting, previously not found using other therapies.
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Inventors:
Ivan A. Casas
Bo Molstam
Bo Molstam
Application Number:
JP2010160577A
Publication Date:
January 25, 2012
Filing Date:
July 15, 2010
Export Citation:
Assignee:
Biogaia AB
International Classes:
A23L2/38; A61K9/10; A61K35/74; A61K9/19; A61K9/48; A61K35/747; A61P1/12; C12N1/20; C12R1/225
Domestic Patent References:
| JP2503385A |
Foreign References:
| US5480641 |
Other References:
RUIZ-PALACIOS,G. et al.,Tolerance and fecal colonization with Lactobacillus reuteri in children fed a beverage with a mixtur,PEDIATRIC RESEARCH,1996年 4月 1日,Vol.39, No.4, Part 2,p.184
ISOLAURI,E. et al,A human Lactobacillus strain (Lactobacillus casei sp strain GG) promotes recovery from acute diarrhe,Pediatrics,1991年,Vol.88, No.1,p.90-97
RAZA,S. et al,Lactobacillus GG promotes recovery from acute nonbloody diarrhea in Pakistan,The Pediatric infectious disease journal,1995年,Vol.14, No.2,p.107-111
原田徳蔵他,乳幼児の便通異常に対するビオラクチス散の使用経験,診療と新薬,1985年,Vol.22, No.5,p.1287-1290
WOLF,B.W. et al.,Safety and tolerance of Lactobacillus reuteri in healthy adult male subjects.,Microbial Ecology in Health and Disease,1995年,Vol.8,p.41-50
ISOLAURI,E. et al,A human Lactobacillus strain (Lactobacillus casei sp strain GG) promotes recovery from acute diarrhe,Pediatrics,1991年,Vol.88, No.1,p.90-97
RAZA,S. et al,Lactobacillus GG promotes recovery from acute nonbloody diarrhea in Pakistan,The Pediatric infectious disease journal,1995年,Vol.14, No.2,p.107-111
原田徳蔵他,乳幼児の便通異常に対するビオラクチス散の使用経験,診療と新薬,1985年,Vol.22, No.5,p.1287-1290
WOLF,B.W. et al.,Safety and tolerance of Lactobacillus reuteri in healthy adult male subjects.,Microbial Ecology in Health and Disease,1995年,Vol.8,p.41-50
Attorney, Agent or Firm:
Patent business corporation Odashima patent office