Title:
炎症を治療するための方法
Document Type and Number:
Japanese Patent JP2011523401
Kind Code:
A
Abstract:
Provided are methods and compositions for reducing airway hyperresponsiveness and other inflammatory diseases, disorders and conditions in a mammal by decreasing FIZZ1 (Found in Inflammatory Zone 1) activity. Also provided are methods and compositions for identifying modulators of airway inflammation and/or inhibitors of FIZZ1. The present invention encompasses modulators of airway inflammation and/or inhibitors of FIZZ1 and uses thereof. In addition, the present invention provides methods and compositions for enhancing an immune response based on FIZZ1 protein.
Inventors:
Hang chain
Michael Earl. Baumann
Bruce A. Jacobson
Lawrence Mason
Michael Earl. Baumann
Bruce A. Jacobson
Lawrence Mason
Application Number:
JP2011507620A
Publication Date:
August 11, 2011
Filing Date:
April 29, 2009
Export Citation:
Assignee:
Weiss LRC
International Classes:
A61K45/00; A61K31/7105; A61K39/395; A61K48/00; A61P1/00; A61P1/04; A61P3/00; A61P9/00; A61P9/04; A61P11/00; A61P11/06; A61P11/08; A61P13/12; A61P15/00; A61P17/00; A61P19/02; A61P21/00; A61P25/00; A61P29/00; A61P31/00; A61P31/04; A61P37/02; A61P43/00; C12Q1/68; G01N33/15; G01N33/50; C07K16/18; C12N15/02; C12N15/09; C12N15/113; C12N15/115
Attorney, Agent or Firm:
Yoshinobu Murofushi
High Hoji Koji
Junko Miyazawa
Noh four
High Hoji Koji
Junko Miyazawa
Noh four