Title:
キョウチクトウ属の種又はテベティア属の種の抽出物で神経学的状態を治療する方法
Document Type and Number:
Japanese Patent JP6453791
Kind Code:
B2
Abstract:
A method of treating neurological condition in a subject by administration of an extract, or fraction or sub-fraction thereof, of Nerium species or Thevetia species is provided, wherein the extract, or fraction or sub-fraction thereof, excludes oleandrin and neriifolin. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of the extract, or a fraction or sub- fraction thereof, to a subject. The extract can be present in a pharmaceutical composition.
Inventors:
Otis Sea Addington
Robert A Newman
Robert A Newman
Application Number:
JP2016033219A
Publication Date:
January 16, 2019
Filing Date:
February 24, 2016
Export Citation:
Assignee:
Phoenix Biotechnology Incorporated
International Classes:
A61K36/24; A61K31/56; A61P3/06; A61P3/10; A61P9/00; A61P9/12; A61P25/00; A61P25/14; A61P25/28; A61P25/32; A61P25/34; A61P25/36
Domestic Patent References:
| JP2009502942A | ||||
| JP201070575A |
Foreign References:
| WO2009064657A1 | ||||
| WO2009118441A1 | ||||
| US20080200401 |
Other References:
J. Nat. Prod.,2005年,Vol.68,pp.198-206
J. Food Sci.,2008年,Vol.7 Nr.73,pp.H174-H178
Arch. Pharm. Res.,2009年,Vol.32 No.6,pp.923-932
J. Pharmacol. Sci.,2009年,Vol.111,pp.22-32
薬学雑誌,2004年,Vol.124 No.7,pp.417-424
Mol. Cells,2002年,Vol.13 No.1,pp.5-11
Bullein de la Societe vaudoise des Sciences naturelles,1960年,Vol.67,pp.205-210
Brain Res.,2007年,Vol.1153,pp.221-230
J. Food Sci.,2008年,Vol.7 Nr.73,pp.H174-H178
Arch. Pharm. Res.,2009年,Vol.32 No.6,pp.923-932
J. Pharmacol. Sci.,2009年,Vol.111,pp.22-32
薬学雑誌,2004年,Vol.124 No.7,pp.417-424
Mol. Cells,2002年,Vol.13 No.1,pp.5-11
Bullein de la Societe vaudoise des Sciences naturelles,1960年,Vol.67,pp.205-210
Brain Res.,2007年,Vol.1153,pp.221-230
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi