Title:
ヒト抗体、医薬組成物及び方法
Document Type and Number:
Japanese Patent JP7121724
Kind Code:
B2
Abstract:
Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to Globo H, stage-specific embryonic antigen 3 (SSEA-3) and stage-specific embryonic antigen 4 (SSEA-4) are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as sarcoma, skin cancer, leukemia, lymphoma, brain cancer, glioblastoma, lung cancer, breast cancer, oral cancer, head-and-neck cancer, nasopharyngeal cancer, esophagus cancer, stomach cancer, liver cancer, bile duct cancer, gallbladder cancer, bladder cancer, pancreatic cancer, intestinal cancer, colorectal cancer, kidney cancer, cervix cancer, endometrial cancer, ovarian cancer, testical cancer, buccal cancer, oropharyngeal cancer, laryngeal cancer and prostate cancer.
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Inventors:
Yui, Chu Young-Dar Tony
Chang, Wong Won
Lee, Shu-Yui
Rye, Jien-Scene
Chen, E-Jui
Chang, Wong Won
Lee, Shu-Yui
Rye, Jien-Scene
Chen, E-Jui
Application Number:
JP2019504699A
Publication Date:
August 18, 2022
Filing Date:
July 31, 2017
Export Citation:
Assignee:
Obey Pharma, Incorporated
International Classes:
C07K16/30; A61K39/395; A61K45/00; A61K47/16; A61K47/68; A61K49/00; A61K49/16; A61K51/10; A61P43/00; G01N33/53; G01N33/574
Foreign References:
| US20160102151 |
Attorney, Agent or Firm:
Kawaguchi International Patent Office
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