Title:
ヒトインターフェロン―β2/インターロイキン―6受容体
Document Type and Number:
Japanese Patent JP3542127
Kind Code:
B2
Abstract:
Human natural IFN- beta 2/IL-6 receptor and its soluble extracellular fragment are provided in substantially purified form and are shown to stimulate and to enhance beneficial effects of IFN- beta 2/IL-6, such as its antiproliferative activity. Polyclonal and monoclonal antibodies raised against the soluble fragment of the receptor are also provided.
Inventors:
Daniella Novic
Louise Chen
Hartmut Engelmann
Michelle level
Menachem Rubin Stain
David Wallac
Louise Chen
Hartmut Engelmann
Michelle level
Menachem Rubin Stain
David Wallac
Application Number:
JP14423590A
Publication Date:
July 14, 2004
Filing Date:
June 01, 1990
Export Citation:
Assignee:
Yeda Research and Development Company Limited
International Classes:
G01N33/53; A61K38/00; A61K38/21; A61K39/395; A61P35/00; C07K1/18; C07K1/20; C07K1/22; C07K14/00; C07K14/52; C07K14/54; C07K14/555; C07K14/565; C07K14/705; C07K14/715; C07K16/00; C12N15/12; C12P21/00; C12P21/08; G01N33/577; C12R1/91; (IPC1-7): C07K14/47; A61K38/00; A61P35/00
Domestic Patent References:
| JP2288898A |
Other References:
Science,241,P.825-827(1988.8.12)
Nature,332,P.83-85(1988)
Cell,vol.58(1989)P.573-581
The Journal of Experimental Medicine,Vol.170,No.5(1989)P.1649-1669
Biochem.Biophs.Res.Commun.,Vol.154,No.1(1988)P.372-379
Nature,332,P.83-85(1988)
Cell,vol.58(1989)P.573-581
The Journal of Experimental Medicine,Vol.170,No.5(1989)P.1649-1669
Biochem.Biophs.Res.Commun.,Vol.154,No.1(1988)P.372-379
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Utamon Shoji
Hajime Asamura
Naganuma Akio
Utamon Shoji