Title:
HUMANIZED ANTIBODY AGAINST HUMAN TISSUE FACTOR(TF) AND METHOD FOR PRODUCING THE HUMANIZED ANTIBODY
Document Type and Number:
Japanese Patent JP2007186522
Kind Code:
A
Abstract:
To provide a method for producing a natural humanized antibody.
The natural humanized antibody has a nonhuman-derived complementarity determining region(CDR) and a natural human antibody-derived framework region(FR) and is reduced in immunogenicity. The method for producing the above antibody is also provided.
Inventors:
SATO ISAO
ADACHI HIDEKI
YABUTA HISAHIRO
ADACHI HIDEKI
YABUTA HISAHIRO
Application Number:
JP2007047091A
Publication Date:
July 26, 2007
Filing Date:
February 27, 2007
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD
International Classes:
C07K16/18; A61K39/395; A61P7/02; A61P43/00; C12N15/09
Attorney, Agent or Firm:
Takashi Ishida
Jun Tsuruta
Fukumoto product
Masaya Nishiyama
Jun Tsuruta
Fukumoto product
Masaya Nishiyama