ヒドラゾノ-マロニトリル類 - Merck Patent Gesellschaft mit beschraenkter Haftung

Title:

ヒドラゾノ-マロニトリル類

Document Type and Number:

Japanese Patent JP5116940

Kind Code:

B2

Abstract:

Hydrazono-malonitrile derivatives of the formula (I) in which R1, R2, R3, R3' and R4 have the meanings given in Claim 1 act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumors, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes mellitus, inflammatory processes, allergies, asthma, autoimmune diseases, myocardial diseases and AIDS.

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Inventors:

Egenweiler, Hans-Michael
Wolf, Michael
Bahia, Norbert
Schwerin, Pile
Ahling, Thomas

Application Number:

JP2003541839A

Publication Date:

January 09, 2013

Filing Date:

October 10, 2002

Export Citation:

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Assignee:

Merck Patent Gesellschaft mit beschraenkter Haftung

International Classes:

C07D237/04; A61K31/50; A61K31/501; A61K45/08; A61P1/04; A61P3/10; A61P9/04; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P19/10; A61P25/00; A61P27/16; A61P29/00; A61P31/18; A61P37/08; C07D403/12

Domestic Patent References:

JP2001503022A

Foreign References:

US5684151
WO2000059484A2
WO2000026201A2
WO1999065880A2
WO2000059890A1

Other References:

J.Med.Chem.,1995年,Vol.38,p.4878-4879

Attorney, Agent or Firm:

Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata
Ohta Kengaku

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