Title:
HYDROGELATION AGENT AND HYDROGEL COMPOSED OF GLYCOSIDE- AMINO ACID DERIVATIVE
Document Type and Number:
Japanese Patent JP3693979
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To obtain a hydrogelation agent and a functional gel having biodegradability or biocompatibility and composed of a low-molecular material as opposed to a gel derived from a polymer.
SOLUTION: The hydrogelation agent comprises a glycoside-amino acid derivative represented by formula (1) {wherein, SG denotes a sugar structural site having a glycoside structure of N-acetylated monosaccharides or disaccharides; AA denotes an amino acid structural site represented by formula (2) [wherein, (n) is 1 or 2; and R denotes a hydrocarbon group represented by any of formulae (3) to (6) such as a hexylmethyl]; and L denotes a linker site connecting the sugar structural site to the amino acid structural site and having a hydrogen bonding functional group or atomic group}. A hydrogel is obtained by including an aqueous liquid in the hydrogelation agent. Thereby, the resultant temperature-sensitive gel reversibly swells or shrinks according to a temperature change.
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Inventors:
Hamaji
Seiji Shinkai
Shigeki Kiyonaka
Seiji Shinkai
Shigeki Kiyonaka
Application Number:
JP2002136434A
Publication Date:
September 14, 2005
Filing Date:
May 13, 2002
Export Citation:
Assignee:
Japan Science and Technology Agency
International Classes:
A61L31/00; C09K3/00; (IPC1-7): C09K3/00
Domestic Patent References:
| JP2000229992A | ||||
| JP200349154A | ||||
| JP2002265428A | ||||
| JP6100581A | ||||
| JP200285957A |
Attorney, Agent or Firm:
Satoshi Tsutsui