疎水性修飾ペプチドおよび肝臓特異的標的化のためのその使用

Japanese Patent JP6486004

B2

The present invention relates to hydrophobic modified peptides for the specific delivery of compounds to the liver, preferably to hepatocytes, in vitro as well as in vivo. The present invention relates to pharmaceutical compositions comprising said hydrophobic modified peptide(s) and the compound(s) to be specifically delivered to the liver. The present invention furthermore relates to the use of the inventive hydrophobic modified peptides as well as to a method for the prevention and/or treatment of liver diseases or disorders.

JP2696116	[Title of Invention] A peptide that reacts with serum of a non-A non-B hepatitis patient with an antigen-antibody reaction, and a DNA encoding the peptide
WO/2024/079311	MODIFIED LONG PEPTIDES SUITABLE FOR USE IN IMMUNISATION
WO/2019/115816	HEPATITIS B IMMUNISATION REGIMEN AND COMPOSITIONS

Walter Meer
Stephan Urban
Stephan Mehle
Uwe Havelcorn

JP2013552977A

March 20, 2019

February 10, 2012

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Ruprecht-Karls-Universitaet Heidelberg

C07K14/02; A61K31/426; A61K31/43; A61K31/436; A61K31/44; A61K31/4706; A61K31/5383; A61K31/65; A61K31/706; A61K38/16; A61K45/00; A61K45/06; A61K47/42; A61K47/50; A61K51/08; A61P1/16; A61P3/00; A61P3/04; A61P3/10; A61P31/12; A61P31/14; A61P31/20; A61P33/02; A61P33/06; A61P33/12; A61P35/00; A61P43/00

Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita

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