Title:
治療剤としてのヒドロキサメート
Document Type and Number:
Japanese Patent JP4243628
Kind Code:
B2
Abstract:
The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
Inventors:
Burner, Eric Jay.
Sendzick, martin
Bascaran, Chitra
Buggy, Joseph Jay.
Robinson, James
Sendzick, martin
Bascaran, Chitra
Buggy, Joseph Jay.
Robinson, James
Application Number:
JP2006509735A
Publication Date:
March 25, 2009
Filing Date:
April 06, 2004
Export Citation:
Assignee:
Pharma Cyclic, Incorporated
International Classes:
C07C259/10; A61K31/165; A61K31/18; A61K31/33; A61K31/34; A61K31/381; A61K31/4015; A61K31/4025; A61K31/4415; A61K31/4525; A61K41/00; A61K45/06; A61P1/16; A61P31/12; A61P35/00; A61P35/02; A61P43/00; C07D207/12; C07D207/327; C07D207/34; C07D209/08; C07D209/18; C07D209/42; C07D209/44; C07D211/46; C07D213/56; C07D213/74; C07D213/81; C07D213/82; C07D215/08; C07D215/18; C07D215/48; C07D215/54; C07D217/04; C07D217/06; C07D217/26; C07D231/56; C07D235/06; C07D235/24; C07D241/52; C07D249/18; C07D261/18; C07D263/58; C07D277/30; C07D277/42; C07D277/56; C07D277/68; C07D307/54; C07D307/68; C07D307/79; C07D307/81; C07D307/85; C07D307/86; C07D317/60; C07D333/16; C07D333/24; C07D333/28; C07D333/38; C07D333/70; C07D405/06; C07D405/12; C07D409/04; C07D413/12; C07D417/04; C07D417/12; C07D207/32
Foreign References:
| WO2001038322A1 | ||||
| WO2003013493A1 |
Other References:
J. Med. Chem.,1999年,Vol.42, No.22,p.4669-4679
TRENDS in Endocrinology & Metabolism,2001年,Vol.12, No.7,p.294-300
J. Med. Chem.,1977年,Vol.20, No.7,p.965-967
TRENDS in Endocrinology & Metabolism,2001年,Vol.12, No.7,p.294-300
J. Med. Chem.,1977年,Vol.20, No.7,p.965-967
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Kazuhiro Nakamura
Tatsunori Ikeda
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Kazuhiro Nakamura
Tatsunori Ikeda